Center for Craniofacial Regeneration

The Center for Craniofacial Regeneration (CCR) develops tissue engineering-based treatments for wounds and defects of the face and skull. These bioengineering technologies aim to restore function as well as appearance in some of the most varied and complex structures of the human body. A global leader in the rapidly-evolving field of craniofacial repair and regeneration, the CCR’s strength lies in its synergistic approach to translational research by clinicians, engineers and basic scientists.

Rich in resources and boasting a talented and diverse team of scientists and clinicians, the Center for Craniofacial Regeneration is a vibrant intellectual environment committed to the academic excellence and career development of faculty, clinicians, post-docs, fellows, undergraduate and graduate students, and visiting scholars. The expertise of our cell and molecular biologists, polymer chemists, material scientists, bioengineers and clinicians allows the innovative employment of therapeutic systems from the molecular to the tissue level. The Center encourages the transfer of developed technologies and treatments to enable new biotechnology ventures providing jobs and foster regional economic development.

Center for Craniofacial Regeneration Mission

The CCR is dedicated to the development of technologies and clinical therapies for craniofacial repair and regeneration. Our center of excellence is a global leader in this rapidly developing field. Our strength lies in the synergistic approach to translational research by clinicians, engineers and basic scientists. To meet these challenges, the CCR strives to foster multidisciplinary approaches to regenerate mineralized and soft tissues of craniofacial structures and employ tissue engineered strategies such as cellular therapies, biomaterials and mechanobiology.


Michigan-Pittsburgh-Wyss Resource Center

The Center for Craniofacial Regeneration is a leader in the National Institutes of Health-funded Michigan-Pittsburgh-Wyss Resource Center: Supporting Regenerative Medicine in Dental, Oral and Craniofacial Technologies. Over the next three years, this translational-focused resource center will pair the most viable dental, oral and craniofacial regeneration therapies with those in the clinical, academic and private sectors to bring cutting edge discoveries into clinical practice. The resource center, with funding totaling about $14 million, is one of only two receiving support this year from the National Institute of Dental and Craniofacial Research (NIDCR). Center for Craniofacial Regeneration Director, Dr. Charles Sfeir, serves as  principal investigator at the resource center’s University of Pittsburgh site.

For detailed infomration about this research, please see the press release.


News and Events

DOD Grant Received

The University of Pittsburgh School of Dental Medicine Center for Craniofacial Regeneration/McGowan Institute for Regenerative Medicine and the U.S. Army Institute of Surgical Research have been awarded A Department of Defense (DOD) grant for $2.1 million to study accelerated bone healing.

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